Multi-Agent System Architecture
VigyanLLM is built on a three-agent architecture designed for sovereign biomedical AI. Each agent has a distinct responsibility, and outputs flow sequentially through orchestration, domain reasoning, and verification before reaching the researcher.
Agent 01 — Core Orchestration
Parses research intent, decomposes complex biological queries into sub-tasks, routes work to the appropriate specialist, and synthesizes outputs into a coherent final report. The orchestration layer ensures every request is handled systematically.
Agent 02 — SubBrain Domain Reasoning
The domain specialist. Handles biological knowledge retrieval, sequence analysis, protein structure prediction, molecular pathway mapping, and clinical reasoning using 320,000+ purpose-built biomedical records across 46 specialized training batches.
Agent 03 — ChinhAI Verification
The validation gate. Cross-checks every output against physics-based benchmarks, off-target databases, and thermodynamic models before release. No single model has the final word — every result is verified before the researcher sees it.
Platform Capabilities
🧬 Primer & PCR Design
Automated design with 24-step thermodynamics validation, BLAST specificity checking, and off-target screening for laboratory protocols.
🔬 Protein Structure
Predict accurate 3D protein conformations and identify structural anomalies for drug target discovery using AlphaFold, RosettaFold, and ESMFold.
💊 Molecular Docking
GPU-accelerated docking with realistic binding energy calculations and interaction surface mapping. Vina-GPU with -8.5 kcal/mol benchmarks.
📊 Gene Expression
RNA-Seq analysis and pathway integration for complete systems biology understanding using DESeq2, edgeR, KEGG, and Reactome.
✂️ CRISPR Analysis
sgRNA-DNA heteroduplex instability analysis and PAM variation mapping for precise genome editing with HNH domain validation.
🏥 Clinical Reasoning
Differential diagnosis and symptom mapping trained on 50,000 dedicated clinical reasoning records for research-grade clinical support.